PSMA3 antibody

Cat.#: 114374

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Product Information

  • Product Name
    PSMA3 antibody
  • Documents
  • Description
    PSMA3 Rabbit Polyclonal antibody. Positive IHC detected in human lymphoma tissue. Positive WB detected in human lung tissue, HeLa cells, NIH/3T3 cells. Observed molecular weight by Western-blot: 28kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    20S proteasome antibody; HC8 antibody; Macropain subunit C8 antibody; Proteasome component C8 antibody; PSC3 antibody; PSC8 antibody; PSMA3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of PSMA3 recombinant protein (Accession Number: NM_002788). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    human lung tissue were subjected to SDS PAGE followed by western blot with Catalog No:114374(PSMA3 antibody) at dilution of 1:400

    human lung tissue were subjected to SDS PAGE followed by western blot with Catalog No:114374(PSMA3 antibody) at dilution of 1:400

    Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:114374(PSMA3 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:114374(PSMA3 antibody) at dilution of 1:50 (under 10x lens)

  • Background
    PSMA3(Proteasome subunit alpha type-3) is also named as HC8, PSC8 and belongs to the peptidase T1A family. The proteasome is a multicatalytic protease complex that catalyzes an energy-dependent, extralysosomal proteolytic pathway responsible for selective elimination of proteins with aberrant structures and naturally occurring short-lived proteins related to metabolic regulation and cell cycle progression. It has 2 isoforms produced by alternative splicing.
  • References
    • Just J, Jung T, Friis NA. Identification of an unstable 4-hydroxynoneal modification on the 20S proteasome subunit α7 by recombinant antibody technology. Free radical biology & medicine. 89:786-92. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"