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Product Name
PRR13 antibody
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Description
PRR13 Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue, human prostate cancer tissue. Positive WB detected in MCF-7 cells. Observed molecular weight by Western-blot: ~20 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human; other species not tested.
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Alternative names
DKFZp564J157 antibody; FLJ23818 antibody; proline rich 13 antibody; Proline rich protein 13 antibody; PRR13 antibody; Taxane resistance protein antibody; TXR1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PRR13 recombinant protein (Accession Number: NM_018457). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
MCF-7 cells were subjected to SDS PAGE followed by western blot with Catalog No:114241(PRR13 Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:114241(PRR13 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:114241(PRR13 Antibody) at dilution of 1:50 (under 40x lens)
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Background
PRR13, also named as TXR1, is reported to be a key regulator of the resistance to cytostatica by decreasing the copy number of the proapoptotic gene thrombospondin-1. PRR13 has some isoforms with MW 10 kDa, 15-17 kDa and 19-23 kDa.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"