-
Product Name
Human NDRG1 / CAP43 (His Tag) recombinant protein
- Documents
-
Description
Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking, notably of the Schwann cell, and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulates microtubule dynamics and maintains euploidy.
-
Protein name
Protein NDRG1
-
Protein short names
RTP; N-MYC DOWNSTREAM REGULATED GENE 1; HMSNL; CMT4D; REDUCING AGENTS AND TUNICAMYCIN-RESPONSIVE PROTEIN; DRG1; NICKEL-SPECIFIC INDUCTION PROTEIN CAP43; NMSL; CAP43; DIFFERENTIATION-RELATED GENE 1 PROTEIN; PROTEIN REGULATED BY OXYGEN-1; DRG-1; GC4; NDRL; NDRG1; PROTEIN NDRG1; PROXY1; TDD5; TARG1; N-MYC DOWNSTREAM REGULATED 1; RIT42; N-MYC DOWNSTREAM-REGULATED GENE 1 PROTEIN; PROTEIN NDR1; NDR1
-
Uniprot ID
Q92597
-
Gene Name
NDRG1; CAP43; DRG1; RTP
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the human NDRG1 (Q92597) (Met1-Cys394) was expressed with a polyhistidine tag at the C-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human NDRG1 consists of 401 amino acids and predicts a molecular mass of 43.8 KDa. It migrates as an approximately 43 KDa band in SDS-PAGE under reducing conditions.
-
Purity
> 85 % as determined by SDS-PAGE
-
Validations
Human NDRG1 / CAP43 Protein (His Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"