Human Profilin 2 / PFN2 (His Tag) recombinant protein
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Protein short names
PROFILIN 2; PFN2; D3S1319E; PFL; PFN; PROFILIN II
A DNA sequence encoding the human PFN2 (AAH18049.1) (Met1-Phe140) was expressed with a polyhistidine tag at the N-terminus.
The recombinant human PFN2 consists of 155 amino acids and predicts a molecular mass of 16.9 KDa. It migrates as an approximately 16 KDa band in SDS-PAGE under reducing conditions.
> 90 % as determined by SDS-PAGE
Human Profilin 2 / PFN2 Protein (His Tag) SDS-PAGE
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