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Human Epiregulin/EREG (Fc Tag) recombinant protein

Cat.#: 502525

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Special Price 478.5 USD

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Product Information

  • Product Name
    Human Epiregulin/EREG (Fc Tag) recombinant protein
  • Documents
  • Description
    Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.
  • Protein name
    Proepiregulin
  • Protein short names
    EPIREGULIN; EPR; ER; PROEPIREGULIN; MGC36144; EREG
  • Uniprot ID
    Q61521
  • Gene Name
    Ereg
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human EREG (Q61521) (Val 63-Leu 108) was fused with the Fc region of human IgG1 at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human EREG/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 306 amino acids and has a predicted molecular mass of 33.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhEREG/Fc monomer is approximately 37 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells.
    The ED50 for this effect is typically 2-8 μg/mL.
  • Validations

    Human Epiregulin / EREG Protein (Fc Tag) SDS-PAGE

    Human Epiregulin / EREG Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"