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Product Name
Human PRDM2/RIZ1 recombinant protein
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Description
S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.
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Protein name
PR domain zinc finger protein 2
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Protein short names
E330024L24RIK; RIZ2; RIZ; GM19732; GM1033; RP23-185C16.1; RIZ1; PRDM2; HUMHOXY1; MTB-ZF; 4833427P12RIK; RP5-1177E19.1; ZNFPR1C1; KMT8
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Uniprot ID
Q13029
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Gene Name
PRDM2; KMT8; RIZ
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the N-terminal segment of human PRDM2 (NP_036363.2) (Met 1-Ala 200), containing the SET domian, was expressed, with two additonal amino acids (Gly & Pro) at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PRDM2 consists of 202 amino acids and predicts a molecular mass of 23 kDa. It migrates as an approximately 26 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 96 % as determined by SDS-PAGE
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Validations
Human PRDM2 / RIZ1 Protein SDS-PAGE
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