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Product Name
PPP1CC antibody
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Description
PPP1CC Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in mouse brain tissue, L02 cells. Positive IHC detected in human heart tissue, human liver tissue. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 35 kDa
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Tested applications
ELISA, WB, IHC, IF, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
PP1 Gamma antibody; PP 1G antibody; PPP1CC antibody; PPP1G antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_002710). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:10-1:100
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114145(PPP1CC antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human heart using Catalog No:114145(PPP1CC antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human heart using Catalog No:114145(PPP1CC antibody) at dilution of 1:50 (under 40x lens)
IP Result of anti-PPP1CC (IP:Catalog No:114145, 4ug; Detection:Catalog No:114145 1:500) with mouse brain tissue lysate 3440ug.
Immunofluorescent analysis of HeLa cells using Catalog No:114145(PPP1CC Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
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Background
PPP1CC, also named as PP-1G, belongs to the PPP phosphatase family and PP-1 subfamily. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. It is involved in regulation of ionic conductances and long-term synaptic plasticity. PPP1CC may play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. The antibody is specific to PPP1CC.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"