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Product Name
PKA C-beta-specifc antibody
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Description
PKA C-beta-specifc Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, human brain tissue. Positive IHC detected in human kidney tissue. Observed molecular weight by Western-blot: 35-37kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
DKFZp781I2452 antibody; PKA C beta antibody; PKACB antibody; PRKACB antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_002731). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:113845(PRKACB antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human kidney slide using Catalog No:113845(PRKACB Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human kidney slide using Catalog No:113845(PRKACB Antibody) at dilution of 1:50
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Background
PRKACB, also named as PKA C-beta, belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family and cAMP subfamily. It mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. This antibody is specific to PRKACB.
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