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Product Name
Human ADCYAP1R1 (Fc Tag) recombinant protein
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Description
This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
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Protein name
Pituitary adenylate cyclase-activating polypeptide type I receptor
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Protein short names
PAC1; AI846590; 2900024I10RIK; PACAPR; PACAP RECEPTOR 1; PACAPRI; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE TYPE I RECEPTOR; PAC1R; PACAP-R1; PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 1 RECEPTOR TYPE I HIPHOP; PACAP1-R; PACAP TYPE I RECEPTOR
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Uniprot ID
P41586
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Gene Name
ADCYAP1R1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human ADCYAP1R1 (P41586) extracellular domain (Met 1-Ala 155) was fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human ADCYAP1R1/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 373 amino acids and has a predicted molecular mass of 42 kDa. The reduced monomer migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 88 % as determined by SDS-PAGE
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Validations
Human ADCYAP1R1 Protein (Fc Tag) SDS-PAGE
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