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Product Name
ADCYAP1R1 Polyclonal Antibody
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Description
Polyclonal antibody to ADCYAP1R1
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Tested applications
WB
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Species reactivity
Human
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Alternative names
ADCYAP1R1 antibody; PAC1 antibody; PAC1R antibody; PACAPR antibody; PACAPRI antibody; ADCYAP receptor type I antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human ADCYAP1R1
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - ADCYAP1R1 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using ADCYAP1R1 antibody at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.
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Background
This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"