Phospho-SYT1-S309 pAb

Phospho-SYT1-S309 pAb

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• Material Safety Data Sheets (MSDS)

Polyclonal antibody to Phospho-SYT1-S309

IF

Human, Mouse, Rat

SYT1 antibody; P65 antibody; SVP65 antibody; SYT antibody; synaptotagmin-1 antibody

Rabbit IgG

Antigen: A phospho specific peptide corresponding to residues surrounding S309 of human SYT1

Polyclonal

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.

IF 1:100 - 1:200

May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.