Polyclonal antibody to Phospho-SYT1-S309
Human, Mouse, Rat
SYT1 antibody; P65 antibody; SVP65 antibody; SYT antibody; synaptotagmin-1 antibody
Antigen: A phospho specific peptide corresponding to residues surrounding S309 of human SYT1
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Store at -20℃. Avoid freeze / thaw cycles.
IF 1:100 - 1:200
Immunofluorescence - Phospho-SYT1-S309 pAb
Immunofluorescence analysis of methanol-fixed HeLa cells using Phospho-SYT1-S309 antibody .
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"