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Product Name
PHD2 antibody
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Description
PHD2 Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, MCF7 cells, mouse brain tissue, mouse kidney tissue. Observed molecular weight by Western-blot: 46kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
C1orf12 antibody; DKFZp761F179 antibody; ECYT3 antibody; Egl nine homolog 1 antibody; EGLN1 antibody; HIF PH2 antibody; HIF prolyl hydroxylase 2 antibody; HIFPH2 antibody; HPH 2 antibody; HPH2 antibody; PHD2 antibody; PNAS 137 antibody; SM 20 antibody; SM20 antibody; ZMYND6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PHD2 recombinant protein (Accession Number: BC005369). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:113803(EGLN1 antibody) at dilution of 1:500
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Background
EGLN1(Egl nine homolog 1) is also named as HIF-PH2,HPH-2,PHD2.It is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. EGLN1 plays a critical role in regulating HIF levels in EPO-producing cells in humans(PMID:16407130).Defects in EGLN1 are the cause of familial erythrocytosis type 3 (ECYT3).This antibody is specific to EGLN1.
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