PGAM2 antibody

PGAM2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PGAM2 Rabbit Polyclonal antibody. Positive WB detected in mouse skeletal muscle tissue. Positive IHC detected in human skin tissue, human brain tissue, human heart tissue, human kidney tissue, human liver tissue, human lung tissue, human ovary tissue, human spleen tissue, human testis tissue. Observed molecular weight by Western-blot: 28-29kd

ELISA, WB, IHC

Human, Mouse; other species not tested.

BPG dependent PGAM 2 antibody; PGAM M antibody; PGAM2 antibody; PGAMM antibody; Phosphoglycerate mutase 2 antibody

Rabbit IgG

This antibody was obtained by immunization of PGAM2 recombinant protein (Accession Number: NM_000290). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Phosphoglycerate mutase (PGAM), an important enzyme in the glycolytic pathway, catalyzes the transfer of a phosphate group between the 2 and the 3 positions of glyceric acid. The muscle-specific isoform (type M, PGAM2) of phosphoglycerate mutase (PGAM) is a housekeeping enzyme and it catalyzes the conversion of 3-phosphoglycerate into 2-phosphoglycerate in the glycolysis process to release energy. It is encoded by the Pgam2 gene. In addition, it is demonstrated that PGAM2 locates both in cytoplasm and nuclei, and takes part in the glycometabolism process of cytoplasm and nuclei(PMID: 18499067). Defects in PGAM2 are the cause of glycogen storage disease type 10 (GSD10).