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Peroxiredoxin 3 antibody

Cat.#: 113722

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Special Price 239.0 USD

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Product Information

  • Product Name
    Peroxiredoxin 3 antibody
  • Documents
  • Description
    Peroxiredoxin 3 Rabbit Polyclonal antibody. Positive WB detected in MCF7 cells, HEK-293 cells, HeLa cells, HepG2 cells, Jurkat cells, mouse brain tissue, mouse liver tissue. Positive IHC detected in human breast cancer tissue. Observed molecular weight by Western-blot: 26-28 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    Antioxidant protein 1 antibody; AOP 1 antibody; AOP1 antibody; HBC189 antibody; MER5 antibody; Peroxiredoxin 3 antibody; Peroxiredoxin III antibody; PRDX3 antibody; PRO1748 antibody; Protein MER5 homolog antibody; Prx III antibody; PRX3 antibody; SP 22 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_006793). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:113722(Prx III antibody) at dilution of 1:400

    MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:113722(Prx III antibody) at dilution of 1:400

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:113722(Prx III Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:113722(Prx III Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:113722(Prx III Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:113722(Prx III Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    PRDX3, also named as AOP1, HBC189 and MER5, belongs to the ahpC/TSA family. It is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. The antibody is specific to PRDX3.
  • References
    • Sulpizio M, Falone S, Amicarelli F. Molecular basis underlying the biological effects elicited by extremely low-frequency magnetic field (ELF-MF) on neuroblastoma cells. Journal of cellular biochemistry. 112(12):3797-806. 2011.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"