Human FKBP12/FKBP1A (His Tag) recombinant protein

Cat.#: 501885

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Product Information

  • Product Name
    Human FKBP12/FKBP1A (His Tag) recombinant protein
  • Documents
  • Description
    Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
  • Protein name
    Peptidyl-prolyl cis-trans isomerase FKBP1A
  • Protein short names
    RP11-314N13.2; FKBP12-T1; MFKBP12; FKBP; PKCI2; FKBP1A; FKBP12-T2; FKBP12; FKBP-12; FKBP1; PKC12; MFKBP1; RP23-419G21.5; FKBP-1A; PPIASE; FKBP12C
  • Uniprot ID
    P62942
  • Gene Name
    FKBP1A; FKBP1; FKBP12
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human FKBP12 (NP_463460) (Met 1-Glu 108) was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human FKBP12 consists of 114 amino acids and predicts a molecular mass of 12.9 kDa as estimated by SDS-PAGE.
  • Purity
    > 96 % as determined by SDS-PAGE
  • Validations

    Human FKBP12 Protein (His Tag) SDS-PAGE

    Human FKBP12 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"