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Product Name
Mouse FKBP12/FKBP1A (His Tag) recombinant protein
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Description
Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
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Protein name
Peptidyl-prolyl cis-trans isomerase FKBP1A
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Protein short names
FKBP12-T1; RP11-314N13.2; FKBP12-T2; PKCI2; FKBP; MFKBP12; FKBP1A; FKBP-12; FKBP1; FKBP12; FKBP-1A; FKBP12C; PPIASE; PKC12; RP23-419G21.5; MFKBP1
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Uniprot ID
P26883
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Gene Name
Fkbp1a; Fkbp1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse FKBP1A (NP_032045.1) (Gly 2-Glu 108) was expressed, with a polyhistide tag at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse FKBP1A consisting of 114 amino acids and has a calculated molecular mass of 12.7 kDa.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Mouse FKBP12 / FKBP1A Protein (His Tag) SDS-PAGE
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