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Product Name
PAX2 antibody
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Description
PAX2 Rabbit Polyclonal antibody. Positive IF detected in Embryonic kidney. Positive WB detected in Transfected HEK-293 cells, human brain tissue.
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Tested applications
ELISA, IF, WB
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Species reactivity
Human; other species not tested.
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Alternative names
paired box 2 antibody; Paired box protein Pax 2 antibody; PAX2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PAX2 recombinant protein (Accession Number: NM_003990). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IF: N/A
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Validations
IF result of anti-PAX2(Catalog No:113604) with Embryonic kidney by Dr. Joo-Seop Park.
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:113604(PAX2 Antibody) at dilution of 1:1000
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Background
PAX2 is a transcription factor, primarily expressed during embryonic development. It has a critical role in the development of the urogenital tract, the eyes, and the CNS. It plays a key role during renal development and to act as an oncogene favoring renal tumor growth. PAX2 was suggested as a sensitive and highly specific marker for renal cell carcinoma (RCC).
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References
- Brown AC, Muthukrishnan SD, Oxburgh L. A synthetic niche for nephron progenitor cells. Developmental cell. 34(2):229-41. 2015.
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