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Product Name
PARN antibody
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Description
PARN Rabbit Polyclonal antibody. Positive WB detected in MDA-MB-453s cells, human cerebellum tissue. Positive IHC detected in human endometrial cancer. Observed molecular weight by Western-blot: 74kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
PARN antibody; Deadenylation nuclease antibody; DAN antibody; Deadenylating nuclease antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PARN recombinant protein (Accession Number: NM_002582). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with Catalog No:113586(PARN antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human endometrial cancer using Catalog No:113586(PARN antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human endometrial cancer using Catalog No:113586(PARN antibody) at dilution of 1:100 (under 40x lens)
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Background
PARN represents poly(A)-specific ribonuclease (deadenylation nuclease)
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References
- Galloway JN, Shaw C, Yu P. CGG repeats in RNA modulate expression of TDP-43 in mouse and fly models of fragile X tremor ataxia syndrome. Human molecular genetics. 23(22):5906-15. 2014.
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