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Product Name
OSGEP antibody
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Description
OSGEP Rabbit Polyclonal antibody. Positive WB detected in human heart tissue, PC-3 cells, Raji cells. Positive IF detected in HepG2 cells. Positive IHC detected in human pancreas cancer tissue, human heart tissue, human kidney tissue. Observed molecular weight by Western-blot: 36kd
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FLJ20411 antibody; GCPL1 antibody; hOSGEP antibody; KAE1 antibody; OSGEP antibody; OSGEP1 antibody; PRSMG1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of OSGEP recombinant protein (Accession Number: NM_017807). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:10-1:100
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Validations
human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:113437(OSGEP antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:113437(OSGEP antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:113437(OSGEP antibody) at dilution of 1:50 (under 40x lens)
Immunofluorescent analysis of HepG2 cells, using OSGEP antibody Catalog No:113437 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
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Background
OSGEP(O-sialoglycoprotein endopeptidase) is also named as hOSGEP, GCPL1 and belongs to the KAE1 / YgjD family. The deduced 335-amino acid OSGEP protein has a predicted molecular mass of 36.4 kDa. It is a protease whose target is O-linked sialic acid-containing glycoproteins, such as episialin(PMID:10859271). It is involved in the metabolism of glycated proteins as a glycoprotein-related chaperon protease(PMID: 20824107).
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