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Product Name
ORAI1 antibody
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Description
ORAI1 Mouse Monoclonal antibody. Positive WB detected in HL-60 cells, A375 cells. Observed molecular weight by Western-blot: 32 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of ORAI1 recombinant protein (Accession Number: NM_032790). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
HL-60 cells were subjected to SDS PAGE followed by western blot with Catalog No:107436(ORAI1 Antibody) at dilution of 1:1000
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Background
Store-operated calcium channels (Socs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of Socs. Orai1 protein is a 32-55 kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combinaed immunodeficiency (SCID) syndrome possess point mutations in Orai1 gene.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"