Human OBCAM/OPCML (His Tag) recombinant protein

Cat.#: 500352

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Product Information

  • Product Name
    Human OBCAM/OPCML (His Tag) recombinant protein
  • Documents
  • Description
    Opioid-binding Cell Adhesion Molecule (OBCAM), also known as OPCML, is a GPI-anchored cell adhesion molecule in the plasma membrane. This neuron-specific protein, consists of three immunoglobulin (Ig)-like domains anchored to the membrane through a glycosylphosphatidylinositol (GPI)-tail. OPCML also belongs to the member of the IgLON family, a subgroup of the immunoglobulin superfamily, consisting of three members, LAMP, OBCAM, and Neurotrimin. These molecules interact homophilically and heterophilically within the family, and OBCAM acts only as heterodimers with LAMP or Neurotrimin and possibly inhibits neurite outgrowth from cerebellar granule cells. OBCAM has been presumed to play a role as a cell adhesion/recognition molecule. Furthermore, the OPCML protein defects may play an important role in the carcinogenesis of cervical or ovarian cancers, and this gene is regarded as a candidate TSG (tumor suppressor gene).
  • Protein name
    Opioid binding protein/cell adhesion molecule-like preprotein isoform a
  • Protein short names
    IGLON1; OPCM; 3732419F12; GM181; AI844366; OBCAM; OPCML; C230027C17; MGC99974; B930023M13RIK; 2900075O15RIK
  • Uniprot ID
    Q14982
  • Gene Name
    OPCML; hCG_1811667
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human OPCML precursor (NP_002536.1) (Met 1-Asn 322) was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The mature recombinant human OPCML consists of 306 amino acids and has a calculated molecular mass of 34 kDa. As a result of glycosylation, rhOPCML migrates as an approximately 55-60 kDa protein in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Validations

    Human OBCAM / OPCML Protein (His Tag) SDS-PAGE

    Human OBCAM / OPCML Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"