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Product Name
Human OSMR/IL-31RB (His Tag) recombinant protein
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Description
Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.
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Protein name
Oncostatin-M-specific receptor subunit beta
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Protein short names
IL-31RB; OSMR; MGC75127; IL-31R SUBUNIT BETA; MGC150627; OSMRB; IL-31R-BETA; PLCA1; MGC150626
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Uniprot ID
Q99650
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Gene Name
OSMR; OSMRB
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human OSMR (NP_003990.1) extracellular domain (Met 1-Met 740) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human OSMR comprises 724 amino acids and has a predicted molecular mass of 82.6 kDa. As a result of glycosylation, rh OSMR migrates as an approximately 130-140 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 96 % as determined by SDS-PAGE
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Validations
Human OSMR / IL31RB Protein (His Tag) SDS-PAGE
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