Human ULBP2 (Fc Tag) recombinant protein

Cat.#: 501821

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Product Information

  • Product Name
    Human ULBP2 (Fc Tag) recombinant protein
  • Documents
  • Description
    NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein which belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway.
  • Protein name
    NKG2D ligand 2
  • Protein short names
    N2DL2; ULBP2; RAET1H; UNQ463/PRO791
  • Uniprot ID
    Q9BZM5
  • Gene Name
    ULBP2; N2DL2; RAET1H; UNQ463/PRO791
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human ULBP2 (Q9BZM5) (Met 1-Ser 217),without the pro peptide, w was fused with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human ULBP2/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 433 amino acids and has a predicted molecular mass of 48.7 kDa. As a result of glycosylation, the apparent molecular mass of rhULBP2/Fc monomer is approximately 58 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Validations

    Human ULBP2 / N2DL-2 Protein (Fc Tag) SDS-PAGE

    Human ULBP2 / N2DL-2 Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"