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Product Name
Human ULBP2/N2DL2/RAET1H/UNQ463/PRO791 (Fc tag) recombinant protein
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Description
NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.
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Protein name
UL16 binding protein 2(ULBP2)
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Protein short names
N2DL2; RAET1H; UNQ463; PRO791
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Uniprot ID
Q9BZM5
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ULBP2/N2DL2/RAET1H/UNQ463/PRO791 Gly26-Ser217 is expressed with a Fc tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ULBP2/N2DL2/RAET1H/UNQ463/PRO791 (Fc tag) recombinant protein
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