-
Product Name
Human ULBP2 (His Tag) recombinant protein
- Documents
-
Description
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein which belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway.
-
Protein name
NKG2D ligand 2
-
Protein short names
N2DL2; ULBP2; RAET1H; UNQ463/PRO791
-
Uniprot ID
Q9BZM5
-
Gene Name
ULBP2; N2DL2; RAET1H; UNQ463/PRO791
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human ULBP2 (Q9BZM5) (Met 1-Ser 217), without the pro peptide, was fused with a polyhistidine tag at the C-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human ULBP2 consists of 203 amino acids and has a predicted molecular mass of 23.2 kDa. As a result of glycosylation, the apparent molecular mass of rh ULBP2 is approximately 33 kDa in SDS-PAGE under reducing conditions.
-
Purity
> 97 % as determined by SDS-PAGE
-
Validations
Human ULBP2 / N2DL-2 Protein (His Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"