Human CD112/Nectin-2/PVRL2 (Fc Tag) recombinant protein

Cat.#: 501328

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Product Information

  • Product Name
    Human CD112/Nectin-2/PVRL2 (Fc Tag) recombinant protein
  • Documents
  • Description
    Probable cell adhesion protein.
  • Protein name
    Nectin-2
  • Protein short names
    CD112; AI987993; MPH; PVRR2; PRR2; PVS; HVEB; PVRL2; PVR; NECTIN-2; AI325026; MHVEB
  • Uniprot ID
    Q92692
  • Gene Name
    PVRL2; HVEB; PRR2
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain (Met 1-Leu 360) of human CD112 (NP_002847.1) was fused with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant mature human CD112/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 567 amino acids and has a calculated molecular mass of 62.3 kDa. As a result of glycosylation, the rh CD112/Fc monomer migrates as an approximately 70-80 kDa protein in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA.
    Immobilized recombinant human CD112 at 20 μg/ml (100 μl/well) can bind biotinylated DNAM1 with a linear range of 0.078-5 μg/ml.
  • Validations

    Human CD112 / Nectin-2 / PVRL2 Protein (Fc Tag) SDS-PAGE

    Human CD112 / Nectin-2 / PVRL2 Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"