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Product Name
Human CD112/Nectin-2/PVRL2 (Fc Tag) recombinant protein
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Description
Probable cell adhesion protein.
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Protein name
Nectin-2
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Protein short names
CD112; AI987993; MPH; PVRR2; PRR2; PVS; HVEB; PVRL2; PVR; NECTIN-2; AI325026; MHVEB
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Uniprot ID
Q92692
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Gene Name
PVRL2; HVEB; PRR2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain (Met 1-Leu 360) of human CD112 (NP_002847.1) was fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant mature human CD112/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 567 amino acids and has a calculated molecular mass of 62.3 kDa. As a result of glycosylation, the rh CD112/Fc monomer migrates as an approximately 70-80 kDa protein in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
Immobilized recombinant human CD112 at 20 μg/ml (100 μl/well) can bind biotinylated DNAM1 with a linear range of 0.078-5 μg/ml. -
Validations
Human CD112 / Nectin-2 / PVRL2 Protein (Fc Tag) SDS-PAGE
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