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Product Name
Mouse CD112/Nectin-2/PVRL2 (His Tag) recombinant protein
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Description
Probable cell adhesion protein.
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Protein name
Nectin-2
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Protein short names
PVRL2; PVR; NECTIN-2; MHVEB; AI325026; CD112; MPH; AI987993; PVS; PRR2; HVEB; PVRR2
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Uniprot ID
Q80XJ5
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Gene Name
Pvrl2; Mph; Pvr; Pvs
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse PVRL2 (NP_033016.3) extracellular domain (Met 1-Gly 351) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse PVRL2 comprises 331 amino acids with a predicted molecular mass of 36 kDa. As a result of glycosylation, it migrates as an approximately 40-45 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 98 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
1. Immobilized mouse CD112-His (Cat: 501275) at 10 μg/ml (100 μl/well) can bind biotinylated mouse DNAM1-His (Cat: 502060) with a linear range of 0.156-5.0 μg/ml.
2. Immobilized mouse CD112-His (Cat: 501275) at 10 μg/ml (100 μl/well) can bind mouse DNAM1-Fc (Cat: 503730) with a linear range of 0.03-1.0 μg/ml. -
Validations
Mouse CD112 / Nectin-2 / PVRL2 Protein (His Tag) SDS-PAGE
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