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Product Name
NECAB3 antibody
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Description
NECAB3 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, rat brain tissue. Positive IHC detected in human pancreas tissue. Observed molecular weight by Western-blot: 40-44 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
APBA2BP antibody; dJ63M2.4 antibody; dJ63M2.5 antibody; EFCBP3 antibody; NECAB3 antibody; Nek2 interacting protein 1 antibody; NIP1 antibody; STIP3 antibody; SYTIP2 antibody; X11L binding protein 51 antibody; XB51 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of NECAB3 recombinant protein (Accession Number: NM_031231). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:113091(NECAB3 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human pancreas using Catalog No:113091(NECAB3 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human pancreas using Catalog No:113091(NECAB3 antibody) at dilution of 1:100 (under 40x lens)
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Background
NECAB3, also named as APBA2BP, NIP1, SYTIP2 and XB51, is a potential substrate of Nek2. NECAB3 inhibits the interaction of APBA2 with beta-amyloid precursor protein (APP). NECAB3 has three isoforms with MW 40 kDa, 44 kDa and 22 kDa.
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References
- Naughton BJ, Duncan FJ, Murrey D. Amyloidosis, synucleinopathy, and prion encephalopathy in a neuropathic lysosomal storage disease: the CNS-biomarker potential of peripheral blood. PloS one. 8(11):e80142. 2013.
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