N-cadherin antibody

N-cadherin antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

N-cadherin Mouse Monoclonal antibody. Positive IHC detected in human heart tissue. Positive WB detected in human heart tissue, pig brain tissue. Observed molecular weight by Western-blot: 120 kDa

ELISA, IHC, WB

Human, Pig, Mouse, Rat; other species not tested.

Cadherin 2 antibody; CD325 antibody; CDH2 antibody; CDHN antibody; CDw325 antibody; N cadherin antibody; NCAD antibody; N-cadherin antibody; Neural cadherin antibody

Mouse IgG1

This antibody was obtained by immunization of N-cadherin recombinant protein (Accession Number: NM_001792). Purification method: Protein G purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin), also known as CDH2 (cadherin 2), is a classical member of the cadherin superfamily which also include E-, P-, R-, and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons, endothelial cells and cardiac myocytes (PMID: 11282032; 9508779; 8125202). N-cadherin has functions in early brain morphogenesis, synaptogenesis and synaptic plasticity (PMID: 23321619).