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Product Name
MRPL48 antibody
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Description
MRPL48 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in Jurkat cells, HeLa cells. Observed molecular weight by Western-blot: 20-21 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CGI 118 antibody; FLJ17047 antibody; FLJ99260 antibody; HSPC290 antibody; L48MT antibody; MRP L48 antibody; MRPL48 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of MRPL48 recombinant protein (Accession Number: NM_016055). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:112832(MRPL48 antibody) at dilution of 1:800
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:112832(MRPL48 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:112832(MRPL48 antibody) at dilution of 1:50 (under 40x lens)
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Background
MRPL48, also named as CGI-118, or HSPC290 is a 212 amino acid protein, which localizes in the Mitochondrion. MRPL48 is a component of the large subunit of the mitochondrial ribosome, including two RNA molecules and, at least, 70 proteins among which 47 proteins for the large subunit. mitochondrial ribosomal protein helps in protein synthesis within the mitochondrion.
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References
- Surovtseva YV, Shadel GS. Transcription-independent role for human mitochondrial RNA polymerase in mitochondrial ribosome biogenesis. Nucleic acids research. 41(4):2479-88. 2013.
- Dalla Rosa I, Durigon R, Pearce SF. MPV17L2 is required for ribosome assembly in mitochondria. Nucleic acids research. 42(13):8500-15. 2014.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"