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Product Name
Mouse Timp1/Timp/Timp-1 recombinant protein
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Description
Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
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Protein name
tissue inhibitor of metalloproteinase 1(Timp1)
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Protein short names
Timp; Timp-1
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Uniprot ID
P12032
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Timp1/Timp/Timp-1 Cys25-Arg205 is expressed.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Timp1/Timp/Timp-1 recombinant protein
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