Mouse Il17f (His tag) recombinant protein

Mouse Il17f (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. Mouse and human IL-17F share 55% sequence identity.IL-17F has been shown to stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. IL-17F is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. Defects in IL-17F are the cause of familial candidiasis type 6 (CANDF6).

interleukin 17F(Il17f)

Q7TNI7

Human Cells

A DNA sequence encoding the Mouse Il17f Arg29-Ala161 is expressed with a 6His tag at the C-terminus.

Mouse

>95% as determined by SDS-PAGE.