-
Product Name
Anti-IL-17F antibody
- Documents
-
Description
Rabbit polyclonal to IL-17F
-
Tested applications
ELISA, WB, IP
-
Species reactivity
Human IL-17F
-
Alternative names
Il17f antibody; IL17F antibody; IL-17F antibody; IL-17F antibody; ML1 antibody; ML-1 antibody; C87042 antibody; IL-24 antibody; interleukin 17F antibody; CANDF6 antibody; cytokine ML-1 antibody; interleukin-24 antibody; mutant IL-17F antibody; interleukin 17F antibody; ML1 antibody; ML-1 antibody; CANDF6 antibody; IL-17F antibody; C87042 antibody; IL-17F antibody
- Immunogen
-
Isotype
Rabbit IgG
-
Preparation
Produced in rabbits immunized with purified, recombinant Human IL-17F (rh IL-17F; NP_443104.1; Arg31-Gln163). IL-17F specific IgG was purified by Human IL-17F affinity chromatography.
-
Clonality
Polyclonal
-
Formulation
0.2 μm filtered solution in PBS
-
Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
WB: 1-10 μg/ml
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human IL-17F.
IP: 4-6 μg/mg of lysate
-
Validations
IL-17F Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
IL-17F Antibody, Rabbit PAb, Antigen Affinity Purified, Immunoprecipitation
-
Background
Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (PubMed:11591732). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation (By similarity).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"