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Product Name
Mouse Dkk1 (His tag) recombinant protein
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Description
This gene encodes a protein that is a member of the dickkopf family. It possesses two clusters of ten cysteine residues separated by a linker region. The protein highly expressed in thyroid, small intestine, stomach, liver, placenta, pancreas, uterus, abdominal cavity, bladder and skin. Weaker expression has been detected in colon and spleen. It antagonizes canonical Wnt signaling by inhibiting LRP5/6interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6.
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Protein name
dickkopf WNT signaling pathway inhibitor 1(Dkk1)
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Uniprot ID
O54908
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Dkk1 Thr32-His272 is expressed with a 8His tag at the N-terminus.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Dkk1 (His tag) recombinant protein
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