Mouse CXCL5 recombinant protein (C-His)
CXCL5 is a small cytokine belonging to the CXC chemokine family. CXC chemokines are particularly significant for leukocyte infiltration in inflammatory diseases. CXCL5 is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. It also can be detected in eosinophils, and can be inhibited with the type II interferon. CXCL5 plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which can be utilized to understand more about pain in other inflammatory conditions like arthritis and cystitis. It stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2.
C-X-C motif chemokine 5
Protein short names
C-X-C motif chemokine 5; Cytokine LIX; Small-inducible cytokine B5 [Cleaved into: GCP-2(1-78; GCP-2(9-78]
A DNA sequence encoding the mouse Cxcl5 (NP_033167.2) (Val45-Ala118) was expressed with a polyhistidine tag at the C-terminus.
The recombinant mouse Cxcl5 consists of 84 amino acids and predicts a molecular mass of 9.4 kDa.
> 95 % as determined by SDS-PAGE.
Mouse CXCL5 Protein (His Tag)
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