Anti-CXCL5 antibody

Anti-CXCL5 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to CXCL5

IHC-P

Human CXCL5

AMCF-II antibody; C-X-C motif chemokine 5 antibody; C-X-C motif chemokine 5 antibody; cytokine LIX antibody; ENA-78 antibody; ENA-78 antibody; ENA-78(1-78) antibody; epithelial-derived neutrophil activating protein 78 antibody; epithelial-derived neutrophil-activating peptide 78 antibody; GCP-2 antibody; granulocyte chemotactic protein-2 antibody; LIX antibody; member 15 antibody; member 5 antibody; member 5 (epithelial-derived neutrophil-activating peptide 78) antibody; neutrophil-activating peptide ENA-78 antibody; neutrophil-activating protein 78 antibody; SCYB5 antibody; Scyb5 antibody; Scyb6 antibody; small inducible cytokine B subfamily antibody; small inducible cytokine B5 antibody; small inducible cytokine subfamily B antibody; small-inducible cytokine B5 antibody; small inducible cytokine subfamily B (Cys-X-Cys) antibody; SCYB5 antibody; ENA-78 antibody; LIX antibody; GCP-2 antibody; Scyb5 antibody; Scyb6 antibody; ENA-78 antibody; AMCF-II antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human CXCL5 (rh CXCL5; P42830; Arg45-Asn114). CXCL5 specific IgG was purified by Human CXCL5 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

CXCL5 is a small cytokine belonging to the CXC chemokine family. CXC chemokines are particularly significant for leukocyte infiltration in inflammatory diseases. CXCL5 is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. It also can be detected in eosinophils, and can be inhibited with the type II interferon. CXCL5 plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which can be utilized to understand more about pain in other inflammatory conditions like arthritis and cystitis. It stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2.

• Dawes JM, et al. (2011) CXCL5 Mediates UVB Irradiation-Induced Pain. Sci Transl Med. 3(90): 90ra60.
• O'Donovan N, et al. (1999) Physical mapping of the CXC chemokine locus on human chromosome 4. Cytogenet. Cell Genet. 84(1-2):39-42.
• Persson T, et al. (2003) Expression of the neutrophil-activating CXC chemokine ENA-78/CXCL5 by human eosinophils. Clin Exp Allergy. 33(4):531-7.