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Product Name
Mouse CRELD1 (Fc Tag) recombinant protein
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Description
CRELD1 is a transmembrane glycoprotein. Epidermal growth factor(EGF)like domain exists in CRELD1. EGF-like repeats are a class of cysteine-rich domains that mediate interactions between proteins of diverse function. EGF domains are found in proteins that are either completely secreted or have transmembrane regions that tether the protein to the cell surface. CRELD1 contains a 333 amino acid acid (aa) extracellular domain (ECD), two tandem transmembrane segments, and a second ECD of 15 aa. Defects in CRELD1 may cause susceptibility to atrioventricular septal defect type 2 which results in a persistent common atrioventricular canal.
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Protein name
Cysteine-rich with EGF-like domains 1
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Protein short names
I11E7 PROTEIN; UNQ188/PRO214; AI843811; CIRRIN; CYSTEINE-RICH WITH EGF-LIKE DOMAIN PROTEIN 1; AVSD2
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Uniprot ID
Q91XD7
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Gene Name
Creld1; mCG_132966
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Creld1 (NP_598691.1) (Met1-Glu362) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Creld1 consists 571 amino acids and predicts a molecular mass of 63 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Mouse CRELD1 Protein (Fc Tag)
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