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Product Name
Mouse APLP1 / Amyloid-like protein 1 (His Tag)
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Description
APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.
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Protein short names
APLP; APLP-1; AMYLOID-LIKE PROTEIN 1; APLP1; AMYLOID BETA (A4) PRECURSOR-LIKE PROTEIN 1; AMYLOID PRECURSOR-LIKE PROTEIN 1
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Uniprot ID
Q3TUB1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Aplp1 (NP_031493.2) (Met1-Glu584) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Aplp1 consists of 557 amino acids and predicts a molecular mass of 62.4 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Mouse APLP1 / Amyloid-like Protein (His Tag)
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