Mouse APLP1 / Amyloid-like protein 1 (His Tag)

Cat.#: 504358

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Product Information

  • Product Name
    Mouse APLP1 / Amyloid-like protein 1 (His Tag)
  • Documents
  • Description
    APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.
  • Protein short names
    APLP; APLP-1; AMYLOID-LIKE PROTEIN 1; APLP1; AMYLOID BETA (A4) PRECURSOR-LIKE PROTEIN 1; AMYLOID PRECURSOR-LIKE PROTEIN 1
  • Uniprot ID
    Q3TUB1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mouse Aplp1 (NP_031493.2) (Met1-Glu584) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse Aplp1 consists of 557 amino acids and predicts a molecular mass of 62.4 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Validations

    Mouse APLP1 / Amyloid-like Protein (His Tag)

    Mouse APLP1 / Amyloid-like Protein (His Tag)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"