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Product Name
Anti-APLP1 antibody
- Documents
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Description
Rabbit Polyclonal to Mouse APLP1
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Tested applications
ELISA, IHC-P
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Species reactivity
Mouse APLP1 / Amyloid-like protein 1
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Alternative names
amyloid beta (A4) precursor-like protein 1 antibody; APLP antibody; APLP1 antibody; APLP-1 antibody; amyloid precursor-like protein 1 antibody; amyloid-like protein 1 antibody; amyloid beta (A4) precursor-like protein 1 antibody; Aplp1 antibody; APLP antibody; APLP-1 antibody; amyloid-like protein 1 antibody; APLP antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with purified, recombinant Mouse APLP1 / Amyloid-like protein 1 . APLP1 / Amyloid-like protein 1 specific IgG was purified by Mouse APLP1 / Amyloid-like protein 1 affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse APLP1 / Amyloid-like protein 1.
IHC-P: 0.01-1μg/mL
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Validations
Mouse APLP1 / Amyloid-like protein 1 Immunohistochemistry(IHC) 15420
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Background
APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.
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