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Product Name
Human APLP1 / Amyloid-like protein 1 (His Tag)
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Description
May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.
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Protein name
Amyloid-like protein 1
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Protein short names
AMYLOID PRECURSOR-LIKE PROTEIN 1; APLP-1; APLP; AMYLOID-LIKE PROTEIN 1; APLP1; AMYLOID BETA (A4) PRECURSOR-LIKE PROTEIN 1
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Uniprot ID
P51693
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Gene Name
APLP1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human APLP1 (P51693-1) (Met1-Glu580) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human APLP1 consists of 553 amino acids and predicts a molecular mass of 61.9 KDa. It migrates as an approximately 67-77 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human APLP1 / Amyloid-like protein 1 Protein (His Tag) SDS-PAGE
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