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Product Name
Mouse Alkaline Phosphatase / ALPL (His Tag) recombinant protein
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Description
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is called dephosphorylation. As the name suggests, alkaline phosphatases are most effective in an alkaline environment. It is sometimes used synonymously as basic phosphatase. Alkaline phosphatases (APs) are ubiquitous in many species, from bacteria to human. Four genes encode AP isoenzymes in humans and rodents. Three AP genes are expressed in a tissue-specific manner (i.e., placental, embryonic, and intestinal AP isoenzymes). Expression of the fourth AP gene is nonspecific to a single tissue and is especially abundant in bone, liver, and kidney. This isoenzyme is also called tissue-nonspecific alkaline phosphatase (TNAP). The enzyme tissue non-specific alkaline phosphatase (TNAP) belongs to the ectophosphatase family. TNAP is present in large amounts in bone in which it plays a role in mineralization.
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Protein name
Alkaline phosphatase
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Protein short names
AKP-2; RP23-277N22.4; HOPS; MGC161443; ALPL; APTNAP; FLJ40094; AKP2; MGC167935; FLJ93059; TNSALP; ALKALINE PHOSPHATASE; AP-TNAP; TNAP
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Uniprot ID
B7XGA6
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Gene Name
Alpl
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Alpl (BAH03518.1) (Met1-Ser502) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Alpl consists 496 amino acids and predicts a molecular mass of 55 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Mouse Alkaline Phosphatase / ALPL Protein (His Tag) SDS-PAGE
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