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Product Name
MMP23B antibody
- Documents
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Description
MMP23B Rabbit Polyclonal antibody. Positive IHC detected in human ovary tumor tissue. Positive FC detected in HepG2 cells. Positive WB detected in A549 cells, HepG2 cells, mouse liver tissue, PC-3 cells. Observed molecular weight by Western-blot: 46-60 kDa
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Tested applications
ELISA, WB, IHC, FC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
Femalysin antibody; matrix metallopeptidase 23B antibody; Matrix metalloproteinase 21 antibody; Matrix metalloproteinase 22 antibody; Matrix metalloproteinase 23 antibody; MIFR antibody; MIFR 1 antibody; MMP 21 antibody; MMP 22 antibody; MMP 23 antibody; MMP21 antibody; MMP22 antibody; MMP23A antibody; MMP23B antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of MMP23B recombinant protein (Accession Number: NM_006983). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
A549 cells were subjected to SDS PAGE followed by western blot with Catalog No:112703(MMP23B antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:112703(MMP23B antibody) at dilution of 1:100 (under 10x lens)
1X10^6 HepG2 cells were stained with 0.2ug MMP23B antibody (Catalog No:112703, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.
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Background
MMP23B(matrix metallopeptidase 23B) is also named as MMP21, MMP22.It is a regulator in matrix remodeling and may be playing a role in enchondral bone formation and in regulation of cranial suture closure .It has 3 isoforms produced by alternative splicing with the molecular weight of 44KDa,48KDa and 46KDa,respectively.It also can be N-glycosylated.
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