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Product Name
MME,CD10 antibody
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Description
MME,CD10 Mouse Monoclonal antibody. Positive IHC detected in human renal cell carcinoma tissue, human kidney tissue, human tonsil tissue. Positive WB detected in pig kidney tissue, mouse kidney tissue. Observed molecular weight by Western-blot: 100 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human, Pig; other species not tested.
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Alternative names
Atriopeptidase antibody; CALLA antibody; CD10 antibody; DKFZp686O16152 antibody; Enkephalinase antibody; EPN antibody; membrane metallo endopeptidase antibody; MME antibody; NEP antibody; Neprilysin antibody; Neutral endopeptidase antibody; Neutral endopeptidase 24.11 antibody
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Isotype
Mouse IgG2b
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Preparation
This antibody was obtained by immunization of MME,CD10 recombinant protein (Accession Number: NM_001354643). Purification method: Caprylic acid/ammonium sulfate precipitation.
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Clonality
Monoclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human renal cell carcinoma using Catalog No:107427(MME,CD10 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human renal cell carcinoma using Catalog No:107427(MME,CD10 antibody) at dilution of 1:100 (under 40x lens)
pig kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:107427(MME,CD10 Antibody) at dilution of 1:1000
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Background
MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).
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