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Product Name
MKP-2 antibody
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Description
MKP-2 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in mouse brain tissue, A549 cells, HepG2 cells, mouse skin tissue, RAW264.7 cells, SMMC-7721 cells. Observed molecular weight by Western-blot: 50kd
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
dual specificity phosphatase 4 antibody; DUSP4 antibody; HVH2 antibody; MAP kinase phosphatase 2 antibody; MKP 2 antibody; MKP2 antibody; TYP antibody; VH2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of MKP-2 recombinant protein (Accession Number: NM_001394). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:112668(MKP-2 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:112668(MKP-2 antibody) at dilution of 1:100 (under 10x lens)
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Background
DUSP4, also named as MKP-2, is a member of the mitogen-activated protein (MAP) kinase phosphatase family which has been suggested to play an important role in the feedback control of MAP kinase-mediated gene expression. DUSP4 preferentially inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"