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  • MBNL3 antibody
  • MBNL3 antibody

MBNL3 antibody

Cat.#: 112508

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Product Information

  • Product Name
    MBNL3 antibody
  • Documents
  • Description
    MBNL3 Rabbit Polyclonal antibody. Positive WB detected in mouse skeletal muscle tissue. Positive IHC detected in human skeletal muscle tissue. Observed molecular weight by Western-blot: 38 kDa
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    CHCR antibody; Cys3His CCG1 required protein antibody; FLJ11316 antibody; MBLX antibody; MBLX39 antibody; MBNL3 antibody; MBXL antibody; Muscleblind like protein 3 antibody; Protein HCHCR antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of MBNL3 recombinant protein (Accession Number: BC042090). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:112508(MBNL3 Antibody) at dilution of 1:600

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:112508(MBNL3 Antibody) at dilution of 1:600

    Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using Catalog No:112508(MBNL3 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using Catalog No:112508(MBNL3 Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    MBNL3, also named as Muscleblind-like protein 3 or Cys3His CCG1-required protein, is a 354 amino acid protein, which contains four C3H1-type zinc fingers and belongs to the muscleblind family. MBNL3 localizes in the nucleus and is highly expressed in the placenta. MBNL3 mediates pre-mRNA alternative splicing regulation and plays a role in myotonic dystrophy pathophysiology. MBNL3 could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"