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Product Name
Human MMP19/RASI-1 recombinant protein
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Description
Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
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Protein name
Matrix metalloproteinase-19
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Protein short names
MATRIX METALLOPROTEINASE 18; MMP18; MATRIX METALLOPROTEINASE 19; MATRIX METALLOPROTEINASE RASI; MMP-19; RASI-1; MMP-18; MGC123370
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Uniprot ID
Q99542
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Gene Name
MMP19; MMP18; RASI
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the catalytic domain of human MMP19 (Q99542-1) (Leu101-Gly256) was expressed, with a N-terminal Met.
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Protein Species
Human
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Molecular weight
The recombinant human MMP19 consists of 157 amino acids and predicts a molecular mass of 17.6 KDa. It migrates as an approximately 18 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human RASI-1 / MMP19 Protein SDS-PAGE
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