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Product Name
Matrilin 2 antibody
- Documents
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Description
Matrilin 2 Rabbit Polyclonal antibody. Positive WB detected in NIH/3T3 cells, HEK-293 cells, mouse liver tissue. Observed molecular weight by Western-blot: 120-150 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
MATN2 antibody; Matrilin 2 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Matrilin 2 recombinant protein (Accession Number: NM_030583). Purification method: Antigen Affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with Catalog No:112498(MATN2 antibody) at dilution of 1:800
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Background
The matrilins represent a new family of oligomeric non-collagenous extracellular matrix proteins that are assumed to act as adapter molecules connecting other proteins and proteoglycans in the extracellular matrix (PMID: 17513098). Four matrilins (matrilin-1, -2, -3, and -4) have been identified. They all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled-coil alpha-helical module (PMID: 18386166). Matrilin-1 and matrilin-3 are expressed mainly in cartilage, while matrilin-2 and matrilin-4 show broader tissue distribution. Matrilin-2 is the largest member of the family. It incorporates into loose and dense connective tissue and becomes associated with some basement membranes (PMID: 17513098).
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