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Product Name
MAP4K3 antibody
- Documents
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Description
MAP4K3 Rabbit Polyclonal antibody. Positive WB detected in human skeletal muscle tissue, HeLa cells, human brain tissue. Positive IHC detected in human skeletal muscle tissue, human heart tissue. Observed molecular weight by Western-blot: 100kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
GLK antibody; MAP4K3 antibody; MAPKKKK3 antibody; MEK kinase kinase 3 antibody; MEKKK 3 antibody; RAB8IPL1 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of MAP4K3 recombinant protein (Accession Number: NM_001270425). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
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Validations
human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:112425(MAP4K3 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human skeletal muscle using Catalog No:112425(MAP4K3 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human skeletal muscle using Catalog No:112425(MAP4K3 antibody) at dilution of 1:100 (under 40x lens)
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Background
MAP4K3(Mitogen-activated protein kinase kinase kinase kinase 3) has kinase activity and that it activates JNK but not MAPK1, MAPK3 or MAPK14 through the activation of MAP3K1 and MAP2K4. Endogenous MAP4K3 kinase activity could be stimulated by exposure to ultraviolet radiation or to tumor necrosis factor.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"