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Product Name
LZTS2 antibody
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Description
LZTS2 Rabbit Polyclonal antibody. Positive WB detected in PC-3 cells. Positive IHC detected in human prostate hyperplasia tissue, human kidney tissue. Observed molecular weight by Western-blot: 70-80 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
hLZTS2 antibody; KIAA1813 antibody; LAPSER1 antibody; LZTS2 antibody; Protein LAPSER1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of LZTS2 recombinant protein (Accession Number: NM_001394952). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:112421(LZTS2 Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human prostate hyperplasia tissue slide using Catalog No:112421(LZTS2 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human prostate hyperplasia tissue slide using Catalog No:112421(LZTS2 Antibody) at dilution of 1:50 (under 40x lens)
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Background
LZTS2, also named as KIAA1813 and LAPSER1, is a novel b-Catenin-interacting protein and it regulates the nuclear export of b-Catenin. LZTS2 is a negative regulator of katanin-mediated microtubule severing and release from the centrosome. It is required for central spindle formation and the completion of cytokinesis.
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