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Product Name
LZTFL1 antibody
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Description
LZTFL1 Rabbit Polyclonal antibody. Positive IHC detected in human heart tissue, human testis tissue. Positive IP detected in HEK-293 cells. Positive WB detected in human testis tissue, HEK-293 cells. Observed molecular weight by Western-blot: 35 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FLJ36386 antibody; LZTFL1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of LZTFL1 recombinant protein (Accession Number: NM_020347). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:112419(LZTFL1 antibody) at dilution of 1:500
IP Result of anti-LZTFL1 (IP:Catalog No:112419, 4ug; Detection:Catalog No:112419 1:800) with HEK-293 cells lysate 3000ug.
Immunohistochemistry of paraffin-embedded human testis tissue slide using Catalog No:112419(LZTFL1 Antibody) at dilution of 1:50 (under 40x lens)
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:112419(LZTFL1 Antibody) at dilution of 1:50 (under 40x lens)
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Background
LZTFL1 belongs to the LZTFL1 family. It is an important regulator of BBSome ciliary trafficking and hedgehog signaling. LZTFL1 regulates Ciliary Trafficking of the BBSome and Smoothened.(PMID:22072986)
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References
- Eguether T, San Agustin JT, Keady BT. IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment. Developmental cell. 31(3):279-90. 2014.
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